Dr. Hana's Nasopure Refill Kit contains 40 buffered salt packets & instructions. Each packet weighs 3.75 gm, and contains pharmaceutical grade sodium chloride & sodium bicarbonate. Each packet makes 4 oz of buffered hypertonic solution or 8 oz of isotonic (milder) solution. This kit makes a total of 160 oz of hypertonic solution or 320 oz of milder solution.